Epigenetics and Evolution

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Epigenetics and evolution.

Epigenetic mechanisms traditionally have been studied in the domains of development and disease, but they may also play important roles in ecological and evolutionary processes. In this article, we revisit historical as well as recent studies that indicate significant impacts of epigenetic processes on evolution. Our main focus is DNA methylation, which is a prevalent chemical modification of g...

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A fundamental precept of evolutionary biology is that natural selection acts on phenotypes determined by DNA sequence variation within natural populations. Recent advances in our understanding of gene regulation, however, have elucidated a spectrum of epigenetic molecular phenomena capable of altering the temporal, spatial, and abundance patterns of gene expression. These modifications may have...

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Epigenetics and Evolution: An Overview

After many years of neglect, the developmental aspect of heredity and its place in evolution are now receiving attention. In this overview, I discuss the relationship between epigenetic inheritance (mainly cellular epigenetic inheritance) and biological evolution. I point to six effects and implications of epigenetic inheritance that are important for evolutionary studies: (i) evolution can occ...

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Epigenetics, brain evolution and behaviour.

Molecular modifications to the structure of histone proteins and DNA (chromatin) play a significant role in regulating the transcription of genes without altering their nucleotide sequence. Certain epigenetic modifications to DNA are heritable in the form of genomic imprinting, whereby subsets of genes are silenced according to parent-of-origin. This form of gene regulation is primarily under m...

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The evolution of epigenetics.

1063 www.sciencemag.org SCIENCE VOL 293 10 AUGUST 2001 E pigenetics covers a broad range of effects, and several are discussed in this special issue. But how did epigenetic regulation arise? For RNA-mediated silencing and DNA methylation there is evidence that they have evolved as part of a host defense mechanism against viruses and parasitic DNA.* The substrate—double-stranded RNA (dsRNA)—for ...

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ژورنال

عنوان ژورنال: Integrative and Comparative Biology

سال: 2014

ISSN: 1540-7063,1557-7023

DOI: 10.1093/icb/icu040